IMMUNOTHERAPY: A RICH HISTORY OF DISCOVERY & INNOVATION

1984

1984

Dr. Tak Mak clones the T-cell receptor.

1994

1994

Dr. Tak Mak demonstrates that CTLA4 (protein receptor) is a key regulatory checkpoint in the immune system.

2002

2002

Dr. Pamela Ohashi (above) and Dr. Linh Nguyen demonstrate that tumour-specific T-cells exist and are capable of mounting a response against tumours.

2005

2005

Dr. Pamela Ohashi, Dr. Linh Nguyen (above) and Patty Yen travel to Dr. Steven Rosenberg’s lab in the U.S. to learn techniques to grow tumour-specific T-cells.

2008

2008

Dr. Pamela Ohashi, Dr. Brad Nelson, Dr. Réjean Lapointe and Dr. Jonathan Bramson found the Canadian Cancer Immunotherapy Consortium.

2009

2009

Immune Therapy Program launches at Princess Margaret Cancer Centre.

2013

2013

First adoptive T-cell therapy clinical trial opens in Canada at The Princess Margaret.

2015

2015

Clinical leadership expandes with Dr. Lillian Siu joining the immunotherapy program.

2016

2016

Over 180 active immunotherapy clinical trials are underway at The Princess Margaret, including Canada’s first gene-engineered T-cell trial.

2017

2017

Drs. Naoto Hirano and Marcus Butler treat the first patient with cells engineered to attack tumours, a first in Canada.

Contact Info

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  • 416-946-6560
  • info@thepmcf.ca

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